Focus on our biotech partners

Since its creation, CARBIOS has demonstrated its commitment to working closely with academics to conduct its research and development program. The Company collaborates with leading academic teams in the fields of microbiology, enzymology, molecular biology, bioinformatics, bioprocesses and polymer chemistry, and in particular with teams from the TBI laboratory, a public laboratory for research under the triple supervision of CNRS, INRAE and INSA Toulouse. The strengthening of the Company’s portfolio of innovations in development is partly the result of these collaborations and demonstrates the success of our commitment to partnership projects.

In 2020, CARBIOS announced the set-up of a new strategic alliance with INSA Toulouse through its TBI laboratory to have access to an internationally recognized enzymatic engineering research center working on plastic recycling and biosynthesis. This laboratory, called PoPLaB (Plastic Polymers and Biotechnologies) thus gives a new dimension to its research activities by reinforcing the internalization of its work. It is the culmination of seven years of scientific collaboration that resulted in the two publications in the prestigious journal Nature of the work carried out with TBI.

Research within PoPLaB focuses on enzymes as well as on the enzyme / polymer interface, thus developing fundamental and applied research activities dedicated to biocatalysis.
The research is divided into several areas:

> Discovery of new environmental enzymes capable of depolymerizing plastics
> Characterization of enzymatic performances with respect to the application objective
> Enzymatic engineering to improve their performance (activity, thermostability, yields), with the “rational enzymatic engineering” and “random enzymatic engineering” teams.
> Performance validation during scaling up